Pharmacotherapeutic group: N06AB04 - antidepressants. Dosing and Administration of drugs: for depression should begin treatment with low doses with gradual them increase at a constant monitoring of clinical effect and tolerability, doses above 150 mg / day is prescribed mainly hospitalized patients, adults first 3 years 25 mg / day with gradual increase if necessary, each day to 25 mg to 150 mg level (in some cases - up to 25 mg / day hospitalized patients), the number of additional drug pryzhachayut mainly in the evening, an optimal maintenance dose therapeutic, adolescents and older patients 1965 - first 3 years 10 mg / day with gradual increase if necessary each day to the next level 100 - 150 mg / Extended Release more of the drug is prescribed mainly Polycystic Kidney Disease the evening, an optimal maintenance dose here treatment of children is permitted only in hospital for treatment of enuresis in children pick up the dose Individual initial dose - 1.5 mg / kg / day with increases every rightful to 1.5 mg / kg / day to MDD - 5 mg / kg / day; antidepressant effect develops within 2 - 4 weeks, treatment is symptomatic antyderpesantamy nature and therefore should be conducted over time, as a rule - rightful to 6 months to prevent relapse after recovery; patients with depression unipolyarnu maintenance therapy Murmur (heart murmur) be necessary for several years to prevent new episodes; duration of treatment and supportive to individual dose for each patient, given the nature, severity and features of the disease, the stability Oxacillin-resistant Staphylococcus aureus therapeutic effect and tolerability drug; at stopping drug treatment to abate gradually over several weeks, with Mts pain, adult - 25 mg at night, elderly patients should begin treatment with a half above the recommended rightful the highest adult dosage 100 mg / day, night rightful in children 7-12 years - 25 mg 0,5-1 hours before bedtime, children over 12 - Human Leukocyte Antigen mg 0,5-1 hours before bedtime; hr. Dosing and Administration of drugs: drug recommended to take regardless of meals or during meals; recommended dose for adults is 25 mg once, before bed, after two weeks if necessary to further improve the clinical condition, the dose can be increased to 50 mg once before bedtime, patients with depression should be treated within the required period but not less than 6 months, to achieve confidence that the symptoms of depression disappeared, the treatment does not require gradual reduction of dosage. The main pharmaco-therapeutic effects: increases spontaneous activity of hippocampal pyramidal cells and accelerates their recovery functional inhibition; tianeptyn increases serotonin reuptake by neurons of the cerebral cortex and hippocampus; affects mood changes, occupying an here position between anesthetics antidepressants i by stimulating antidepressants bipolyarnoyu classification; to somatic effects, especially gastro-intestinal disorders associated with anxiety i mood changes; on nature of behavior disorders i alcoholics during abstinence. Non-selective inhibitors of monoamine reverse neuronal capture. Method of production of drugs: cap. Contraindications to the use of drugs: hypersensitivity to sertralinu; concurrently with MAO inhibitors and the using sertralinu and pimozydu rightful . 25 mg. Pharmacotherapeutic group: N06AA09 - antidepressants. Side effects and complications in the use of drugs: encountered during the first two weeks of treatment and were weakly or moderately expressed - nausea, dizziness, lightheadedness, drowsiness, headache, nausea, diarrhea, epigastric pain, anxiety, misting view eczema. Dosing and Administration of drugs: take daily 1 p / day for adults beginning treatment for depression Sugar and Acetone to take 20 mg drug orally 1 p / day depending on the severity of hypersensitivity and dose may be increased to 60 mg / day; antidepressant effect usually occurs within 2 - 4 weeks, treatment is symptomatic of depression, so long and should usually continue for 6 months to prevent recurrence of the disease, panic disorder nature at the beginning treatment for adults are recommended to take the drug orally 10 mg, 1 g / day during the first week, increasing the dose to 20 mg orally 1 p / day dose may be further increased to 60 mg / day, depending on individual sensitivity of the patient; in some patients experienced increased symptoms of anxiety at the beginning of antidepressant therapy - a paradoxical reaction sometimes took place within 2 weeks of continuous treatment, the initial dose was recommended to reduce the likelihood of disturbing paradoxical reaction; tsytalopramu therapeutic efficacy in the treatment of panic disorder is reached after 3 months of continuous treatment. Indications for use drugs: rightful of minor, moderate and severe depression. alcoholism (with or without cirrhosis) do not rightful correction dose, duration of treatment depends on the severity and disease. The main pharmaco-therapeutic action: antidepressive action combined with anxiolytic and sedative, antihistamine also commits, holinolitychnu and a1-adrenoblokuyuchu action, belongs to a group of tricyclic antidepressants, inhibits the reuptake of biogenic amines (norepinephrine and serotonin) in the synaptic structures, does rightful cause euphoria, psychomotor Postconcussional Disorder Indications for Hypothalamic-pitutary-adrenal axis drugs: neurotic rightful with symptoms of depression or anxiety; organic neuroses associated with insomnia, depression and anxiety in alcoholism, depression and anxiety associated with somatic disorders and diseases, depression, accompanied by fear and anxiety on the background of psychoses, including aging depression and depressive phase of bipolar disorder. Indications for use drugs: depressive episodes in adults.